hPOT1-ssDNA Complex

hPOT1V2DNA

 

Recent Publications

  • Borah S., Xi L, Zaug A.J., Powell, N.M., Dancik, G.M., Cohen, S.B., Costello, J.C., Theodorescu , D., Cech, T.R. TERT Promoter Mutations and Telomerase Reactivation in Urothelial Cancer Science, (2015). [Accepted for publication 01.06.2015]
  • Schmidt, J.C., Dalby, A.B. and Cech, T.R. Identification of human TERT elements necessary for telomerase recruitment to telomeres. eLife, 3, (2014).
  • Nandakumar, J., Bell, C.F., Weidenfeld, I., Zaug, A.J., Leinwand, L.A., Cech, T.R. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature, 492: 285-289 (2012).
  • Davidovich, C., Wang, X., Cifuentes-Rojas, C., Goodrich, K.J., Gooding, A.R., Lee, J.T. and Cech, T.R. Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA. Molecular Cell, 57, 552-558, (2015).
  • Schwartz, J.C., Wang, X., Podell, E. R., Cech, T.R. RNA seeds higher-order assembly of FUS protein. Cell Reports 5, 918-925, (2013).